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Fig. 1 | Inflammation and Regeneration

Fig. 1

From: Therapeutic intervention of inflammatory/immune diseases by inhibition of the fractalkine (CX3CL1)-CX3CR1 pathway

Fig. 1

Multiple functions of FKN. Many key functional aspects of the FKN-CX3CR1 axis have been identified: (1) the rapid capture and firm adhesion of immune cells to vascular endothelial cells, (2) chemotaxis, (3) the enhancement of the transmigration to other chemokines, (4) the crawling behavior of the monocytes that patrol on vascular endothelial cells, (5) the retention of monocytes as the accessory cells of the inflamed endothelium to recruit inflammatory cells, and (6) the survival of the macrophage

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Inflammation and Regeneration

ISSN: 1880-8190

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