Fig. 7

rCXCL2 treatment improves visual function in mice with retinal NMDA injury. a Representative pSTR waveforms from normal control eyes, as well as NMDA injection in the vehicle (PBS) or rCXCL2-treated eyes, after 7 days as recorded by flash ERG responses. The pSTR was elicited with a very dim flash stimuli at an intensity of 0.001 cd. s/m² and measured from the baseline to the positive peak of the waveform. b Averaged data of pSTR amplitudes from each group. The results are shown as mean ± SEM, n = 8 eyes per group, *p < 0.05. c Representative PhNR waveforms from each group. The PhNR was elicited with strong light stimuli at the flash intensity of 10.0 cd. s/m² and measured from the baseline to the trough of the negative response following the b wave. d Averaged data of PhNR amplitudes from each group. Data are presented as mean ± SEM, n = 5 eyes per group, *p < 0.05. e Representative OP waveforms from each group recorded with the white flashes of 3.0 cd. s/m² scotopic responses via bandpass filtering between 50 and 170 Hz. f The averaged data of OP (OP1, OP2, and OP3) amplitudes from each group were quantified. The results are shown as mean ± SEM, n = 9 eyes per group, *p < 0.05. g Representative scotopic series (a- and b- waves) in response to the increasing flash intensity from each group. The flash intensities used to elicit the responses are presented to the left. h, i Line chart shows the amplitudes of a- and b- waves in scotopic ERG responses, respectively