Fig. 1From: Autoimmune-mediated astrocytopathyThe pathogenicity of AQP4-IgG. The destruction of BBB induced by CNS-infiltrating T cells allows AQP4-IgG produced by B cells in peripheral blood to get an access to AQP4 expressed on astrocytes, leading to complement-dependent astrocyte damage. Figures were created with biorender.comBack to article page