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Fig. 1 | Inflammation and Regeneration

Fig. 1

From: Autoimmune-mediated astrocytopathy

Fig. 1

The pathogenicity of AQP4-IgG. The destruction of BBB induced by CNS-infiltrating T cells allows AQP4-IgG produced by B cells in peripheral blood to get an access to AQP4 expressed on astrocytes, leading to complement-dependent astrocyte damage. Figures were created with biorender.com

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