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Fig. 4 | Inflammation and Regeneration

Fig. 4

From: Effect of JAK inhibitors on the three forms of bone damage in autoimmune arthritis: joint erosion, periarticular osteopenia, and systemic bone loss

Fig. 4

The effects of the various JAK inhibitors on osteoclastogenesis in a monoculture of osteoclast precursor cells and coculture system of precursors with supporting cells. A Representative TRAP staining (left) and number of TRAP+ multinucleated cells (right) in the presence of the respective JAK inhibitor in the monoculture of osteoclast precursors. B Representative TRAP staining (left) and number of TRAP+ multinucleated cells (right) in the presence of the respective JAK inhibitor in the coculture of osteoclast precursors and osteoblastic cells. Scale bar: (100 μm). All data are expressed as the mean ± SEM. ****p < 0.0001; by one-way ANOVA with the Holm-Sidak multiple comparisons test

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Inflammation and Regeneration

ISSN: 1880-8190

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