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Fig. 1 | Inflammation and Regeneration

Fig. 1

From: Placenta mesenchymal stem cell-derived extracellular vesicles alleviate liver fibrosis by inactivating hepatic stellate cells through a miR-378c/SKP2 axis

Fig. 1

Construction of multicellular liver organoids. A Representative images of four types of cells for the construction of liver organoids (hepatocytes, hepatic stellate cells, Kupffer cells, and liver sinusoidal endothelial cells). B The morphological observation of liver organoids from 4 h to the 45th day. C Determination of liver-specific markers (Albumin, CYP3A4, and CYP450) in liver organoids. D Albumin secretion in liver organoids from the 10th day to the 45th day detected by ELISA. E The growth status of liver organoids from the 10th day to the 45th day detected by 3D viability assay. F Live/dead staining was performed in liver organoids from the 10th day to the 45th day. G H&E staining of liver organoids from the 10th day to the 45th day. HSCs, hepatic stellate cells; ALB, albumin. Bar scale, 50 μm

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Inflammation and Regeneration

ISSN: 1880-8190

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