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Fig. 2 | Inflammation and Regeneration

Fig. 2

From: Analysis of distribution, collection, and confirmation of capacity dependency of small extracellular vesicles toward a therapy for liver cirrhosis

Fig. 2

Uptake of tdTomato expressing small extracellular vesicles (sEVs) into liver constituent cells. A Uptake by macrophages, liver sinusoidal endothelial cells (LSEC), quiescent hepatic stellate cells (HSCs), activated HSCs, and hepatocytes in vitro. Upper panels: normal observation images, lower panels: fluorescence images. 2.0 μg/mL of tdTomato expressing sEVs were added 4 h before the observation. Nuclei were stained with DAPI. Scale bar, 50 μm. n = 3 per experiment. B Magnified view of the macrophages expressing tdTomato sEVs. Scale bar, 20 μm. Left panel: DAPI, middle panel: tdTomato, right panel: merged view

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Inflammation and Regeneration

ISSN: 1880-8190

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