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Fig. 1 | Inflammation and Regeneration

Fig. 1

From: Testosterone upregulates glial cell line-derived neurotrophic factor (GDNF) and promotes neuroinflammation to enhance glioma cell survival and proliferation

Fig. 1

Differential gene expression between the control (untreated) and testosterone-treated U251 and HA. A Next-generation sequencing showing differential gene expression between the untreated group and testosterone-treated U251 (n = 2). We selected the genes that are involved in neuroinflammation only. B Reverse transcription-quantitative polymerization chain reaction (RT-qPCR) comparing GDNF, SOX1, IL-6, COX2, PTGIR, AR, and GFAP between the control (untreated) and testosterone-treated U251 and HA, a for U251 and b for HA (n = 3). C Immunoblotting comparing GDNF protein levels between the control (untreated) and testosterone-treated U251 and HA (n = 3). *p < 0.05, **p < 0.01, ***p < 0.001, and ****p < 0.0001

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