Fig. 3From: Testosterone upregulates glial cell line-derived neurotrophic factor (GDNF) and promotes neuroinflammation to enhance glioma cell survival and proliferationTestosterone upregulates cyclophilin A expression in vitro and in vivo. A Immunoblotting detection of cyclophilin A protein level in U251 and HA (n = 3). B Immunohistochemistry comparing cyclophilin A-positive cells between the untreated and testosterone-treated xenograft tissue (n = 3). C Immunofluorescence comparing GFAP (green) and IBA1 (red) positive inflammatory astrocyte between the untreated and testosterone-treated brain tissue (n = 3). GFAP (green) indicated the total astrocyte and IBA1 of the inflammatory microglia. ***p < 0.001, and ****p < 0.0001Back to article page