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Fig. 5 | Inflammation and Regeneration

Fig. 5

From: Testosterone upregulates glial cell line-derived neurotrophic factor (GDNF) and promotes neuroinflammation to enhance glioma cell survival and proliferation

Fig. 5

Testosterone promotes pro-inflammatory macrophage recruitment and activation. A Immunofluorescence comparing pro-inflammatory macrophages (CD86) and microglial (Iba1) between the untreated and testosterone-treated tumor tissue (n = 3) B Contrast image showing macrophage (Raw264.7) interaction with U251 and HA between the untreated and testosterone-treated groups (n = 4). The white arrow indicates the macrophages and the red arrow indicates U251 or HA. C Contrast image comparing macrophage activation between the untreated and testosterone-treated groups (n = 4). The activated microphage have outgrowth while the non-activated macrophages did not have. **p < 0.01 and ***p < 0.001

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Inflammation and Regeneration

ISSN: 1880-8190

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