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Fig. 6 | Inflammation and Regeneration

Fig. 6

From: Testosterone upregulates glial cell line-derived neurotrophic factor (GDNF) and promotes neuroinflammation to enhance glioma cell survival and proliferation

Fig. 6

The testosterone upregulates pro-inflammatory genes NRF2, ERK1/2, and pERK1/2 protein level and GDNF translocation. A Immunoblotting detection of NRF2, ERK1/2, and pERK1/2 protein levels in U251 and HA (n = 3). B Protein atlas indicating GDNF subcellular location. C Immunofluorescence detection of GDNF subcellular localization in human astrocyte (red) and U251 (green) (n = 4). *p < 0.05 and **p < 0.01

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