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Fig. 1 | Inflammation and Regeneration

Fig. 1

From: Prime-boost-type PspA3 + 2 mucosal vaccine protects cynomolgus macaques from intratracheal challenge with pneumococci

Fig. 1

Nasal antigen administration boosts antigen-specific IgG in serum and IgA in BALF after primary immunization with PspA3 + 2/WOW emulsion containing curdlan + CpG-ODN. A Time course of PspA-specific serum IgG titers after primary immunization (n = 5 mice/group). Results represent mean ± SEM. *P < .05 (WOW + PspA vs. WOW + PspA + Boost),.##P < .01 (WOW + PspA + curdlan + CpG vs. WOW + PspA + curdlan + CpG + boost) (Tukey’s post hoc test). B Titers of PspA-specific IgA in bronchoalveolar lavage fluid (BALF) of mice immunized with PspA/WOW emulsion containing curdlan + CpG-ODN (n = 5 mice/group). Results represent mean ± SEM. *P < .05 (WOW + PspA + curdlan + CpG vs. WOW + PspA + curdlan + CpG + boost) (Tukey’s post hoc test)

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Inflammation and Regeneration

ISSN: 1880-8190

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