Fig. 5From: Prime-boost-type PspA3 + 2 mucosal vaccine protects cynomolgus macaques from intratracheal challenge with pneumococciTime course of body weight, number of white blood cells, level of CRP, and number of bacteria in lung homogenates. A Body weight changes after S. pneumoniae infection are shown. B Numbers of white blood cells (WBCs) are shown. C Levels of C-reactive protein (CRP) are shown. D Numbers of bacteria in lung homogenates were evaluated by colony formation on sheep blood agar plates. CFU, colony-forming units. *P < .05 (vs. WOW). NS, not significant (Tukey’s post hoc test). WOW: n = 2 macaques/group, WOW + PspA + curdlan: n = 3 macaques/group, WOW + PspA + CpG + curdlan: n = 4 macaques/groupBack to article page