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Fig. 5 | Inflammation and Regeneration

Fig. 5

From: Versatile extracellular vesicle-mediated information transfer: intercellular synchronization of differentiation and of cellular phenotypes, and future perspectives

Fig. 5

Schematic of the PSyC mechanism including EV secretion and miR-132 delivery. From fast-differentiating cells, miR-132 is transferred through EVs to surrounding recipient cells, where it inhibits Spry1 and Rasa1 to transmit the signal. As a result, the differentiation mechanism is synchronized in the fast-differentiating cells and recipient cells [53]

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