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Fig. 3 | Inflammation and Regeneration

Fig. 3

From: RANKL system in vascular and valve calcification with aging

Fig. 3

Scheme of plaque calcification. Natural plaque progression involves lipid-pool expansion coupled with micro-calcifications within lipid pools. Micro-calcifications are also commonly found within an overlying fibrous cap. If these micro-calcifications coalesce into speckles and fragments during therapy or atheroma progression, vessel wall stresses may decrease significantly, contributing to plaque stability

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