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Table 1 Candidate populations as lung epithelial stem cells

From: Inflammatory responses in the initiation of lung repair and regeneration: their role in stimulating lung resident stem cells

Populations

Markers

Cell types into which they can differentiate

Basal stem cells (BSCs)

P63+, KRT5+, KRT14+ or −

BLPCs

Basal luminal precursor cells (BLPCs)

P63+, KRT5+, KRT8+

ciliated cells, club cells, neuroendocrine cells

Broncho-alveolar stem cells

CC10+, pro-SPC+

AT II cells, ciliated cells, club cells

ITGα6+, ITGβ4+ alveolar progenitor cells

CC10−, pro-SPC−, ITGα6+, ITGβ4+

AT II cells, club cells

Alveolar type 2 cells (AT II cells)

pro-SPC+

AT I cells

Distal alveolar stem cells (DASCs)

P63+, KRT5+

AT II cells, club cells

Alveolar Epithelial Progenitor cells (AEPCs)

CD90+, pro-SPC+

AT II cells