Fig. 1From: The pathological role of vascular aging in cardio-metabolic disorderThe role of vascular and bone marrow aging in heart failure. Activation of sympathetic nervous system (SNS)/ROS/p53 signaling promotes the interaction between endothelial cells and bone marrow-derived inflammatory cells by the up-regulation of ICAM-1 and integrin expression to exacerbate cardiac dysfunctionBack to article page