Fig. 1From: Applications of reconstituted inflammasomes in a cell-free system to drug discovery and elucidation of the pathogenesis of autoinflammatory diseasesSchematic representation of reconstituted inflammasomes. Once specific ligands are recognized by NLRPs, inflammasomes are constituted. Then, chemical energy of reactive oxygen from donor beads is transferred to acceptor beads and a signal is detectedBack to article page