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Fig. 4 | Inflammation and Regeneration

Fig. 4

From: Effects of acute exposure to low-dose radiation on the characteristics of human bone marrow mesenchymal stromal/stem cells

Fig. 4

Microarray analysis of Ir-MSCs. (a) Venn diagram of the number of genes whose expression levels were downregulated in lots A, B, C, and D of Ir-MSCs compared with non-Ir-MSCs. The purple, green, gray, and orange ellipses represent genes in lots A, B, C, and D, respectively. (b) Pathway analysis was performed of 1495 genes that were downregulated in both lots A and C of Ir-MSCs, but not in lot B or D of Ir-MSCs. The pathway “G1 to S cell cycle control” was significantly enriched. (c) GSEA of genes from lots A, B, C, and D of Ir-MSCs and non-Ir-MSCs using the gene set AMUNDSON_POOR_SURVIVAL_AFTER_GAMMA_RADIATION_2G. NES normalized enrichment score, FDR false discovery rate

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