Fig. 9

Expression of hematopoiesis-associated molecules in Ir-MSCs. (a, b) mRNA expression of various hematopoiesis-associated molecules in lot A of BM-MSCs that were exposed to (Ir-MSCs, white bars) or not exposed to (non-Ir-MSCs, black bars) 0.1 Gy γ-radiation, as assessed by quantitative real-time PCR analysis. Molecules whose expression levels differed between Ir-MSCs and non-Ir-MSCs are shown in (a), whereas those whose expression levels did not differ between Ir-MSCs and non-Ir-MSCs are shown in (b). Expression in Ir-MSCs is shown relative to that in non-Ir-MSCs. Data are mean values ± SD. n = 5 per group. *, p < 0.05; **, p < 0.01. (c) mRNA expression of molecules affected in lot A of BM-MSCs was examined in lot B of BM-MSCs that were exposed to (Ir-MSCs, white bars) or not exposed to (non-Ir-MSCs, black bars) 0.1 Gy γ-radiation, as assessed by quantitative real-time PCR analysis. Data are mean values ± SD. n = 5 per group