Fig. 1
From: Roles of nitric oxide and ethyl pyruvate after peripheral nerve injury
Neuroprotective and neurodegenerative aspects of NO. By activating eNOS (endothelial NO synthase), NO causes neurodegeneration which increases intracellular calcium (Ca2+) level following nNOS (neuronal NO synthase) dephosphorylation and oxidative stress. However, iNOS (inducible NO synthase) inhibitors inhibit peroxynitrite anion which halts cytochrome that maintains homeostasis [55]