Fig. 4From: Deterioration in saliva quality in patients with Sjögren’s syndrome: impact of decrease in salivary epidermal growth factor on the severity of intraoral manifestationsChanges in the salivary flow rate and salivary epidermal growth factor (EGF) output according to the extent of changes in the Oral Health Impact Profile (OHIP)-14 score at 3-year re-evaluation. a Patient group in which the OHIP-14 score decreased or did not change (non-exacerbation group). b Patient group in which the OHIP-14 score increased (exacerbation group). (1) Changes in the salivary flow rate. (2) Changes in the salivary EGF output. Statistical analysis was performed using the Wilcoxon signed-rank test. *p < 0.05; n.s., not significantBack to article page