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Fig. 4 | Inflammation and Regeneration

Fig. 4

From: Deterioration in saliva quality in patients with Sjögren’s syndrome: impact of decrease in salivary epidermal growth factor on the severity of intraoral manifestations

Fig. 4

Changes in the salivary flow rate and salivary epidermal growth factor (EGF) output according to the extent of changes in the Oral Health Impact Profile (OHIP)-14 score at 3-year re-evaluation. a Patient group in which the OHIP-14 score decreased or did not change (non-exacerbation group). b Patient group in which the OHIP-14 score increased (exacerbation group). (1) Changes in the salivary flow rate. (2) Changes in the salivary EGF output. Statistical analysis was performed using the Wilcoxon signed-rank test. *p < 0.05; n.s., not significant

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