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Fig. 2 | Inflammation and Regeneration

Fig. 2

From: CTGF in kidney fibrosis and glomerulonephritis

Fig. 2

Macrophage recruitment in Rosa-CTGF cKO mice with anti-GBM nephritis at the earlier stage. a Representative photomicrographs of the kidneys at 1 week after induction of anti-GBM nephritis (PAS staining). Left upper panel, control mice with anti-GBM nephritis; right upper panel show, Rosa-CTGF cKO mice with anti-GBM nephritis. Bar represents 50 μm. b Immunohistochemical studies for MAC-2 at 1 week after induction of anti-GBM nephritis. Bar represents 50 μm. c Changes in proteinuria at 1 week after induction of anti-GBM nephritis. d The number of MAC-2-positive cells at 1 week after induction of anti-GBM nephritis. Values are expressed as means ± s.e. *P < 0.05, **P < 0.01 vs. control GBM

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