Fig. 2

Comparative genome maps of representative MHC genes in humans and cynomolgus macaques. HLA and Mafa mean human and cynomolgus macaque MHCs, respectively. Orange boxes indicate classical class I genes, HLA-A, HLA-B, HLA-C and their Mafa orthologs (Mafa-A, Mafa-B and Mafa-I), in the class I sub-region, and blue boxes indicate classical class II genes, HLA-DR, HLA-DQ, HLA-DP and their Mafa orthologs (Mafa-DR, Mafa-DQ and Mafa-DP), in the class II sub-region. Numbers under boxes and in parentheses indicate allele numbers reported by the IPD-IMGT/HLA database release 3.31.0 in January 2018 in humans (Available from: https://www.ebi.ac.uk/ipd/imgt/hla/) and the IPD-MHC database release 3.0.0.1 in February 2018 in cynomolgus macaques (Available from: https://www.ebi.ac.uk/ipd/mhc/group/NHP/allele/Mafa)