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Table 3 The total expression ratio of the gene of TGFβ1 in the MEFs treated with various concentrations of ethanol extract of Calendula (5 and 10 μg/ml) relative to control group is presented in each time (12 and 24 h after treatment). The statistic test for significance is randomization re-allocation test, implemented in the relative expression software tool. Significant down or upregulations of the genes highlighted

From: Calendula officinalis stimulate proliferation of mouse embryonic fibroblasts via expression of growth factors TGFβ1 and bFGF

 

12 h after treatment

24 h after treatment

5 μg/ml

10 μg/ml

5 μg/ml

10 μg/ml

Relative expression

1.7

2.3

0.7

0.62

Standard error

± 0.21

± 0.28

± 0.24

± 0.16

P value

0.235

0.001

0.490

0.359

Fold increase/decrease

+ 1.7

+ 2.3

− 1.4

− 1.6