Fig. 3From: Induced pluripotent stem cells representing Nakajo-Nishimura syndromeStrategy of disease modeling and drug discovery using iPS cells. If a major aspect of the disease phenotype is reproduced in vitro using a genetically engineered pair of mutant and wild-type iPS cells (disease modeling), a compound which can recover the phenotype is searched with high-throughput screening and provided for clinical trial following its application to any model mice in vivo (drug discovery)Back to article page