Table 4 Properties of articular cartilage chondrocyte
From: Shear bioreactors stimulating chondrocyte regeneration, a systematic review
Chondrocyte | |
|---|---|
Role | Development, maintenance, and repair of the extracellular matrix (ECM). |
Origin | Mesenchymal stem cells |
Volume | 2% of the total volume of articular cartilage. |
Shape, number, and size | Vary in shape, number, and size, depending on the anatomical regions of the articular cartilage. |
Respond to stimuli | Respond to a variety of mechanical stimuli and growth factors |
Replication | Detectable cell division, limited potential for replication |
Synthesis matrix | Responsible for both the synthesis and the breakdown of the cartilaginous matrix. |
Differentiation | Highly differentiated cell, highly specialized, metabolically active cells |
Adaption by low oxygen | Well adapted by low oxygen consumption to conditions |