From: Shear bioreactors stimulating chondrocyte regeneration, a systematic review
Hz | % strain | Cell proliferation | Collagen | GAG | Proteoglycan | Scaffold | |
---|---|---|---|---|---|---|---|
[15] | 1 | 2 | Chondrocyte | 40% increase | Not measured | 25% increase | (Cpp) calcium poly phosphate |
[16] | 0.01 | 0.4–1.6 | Chondrocyte | 40% increase | Not measured | 25% increase | Cartilage disk |
[17] | 0.1 | 0.5–6 | Chondrocyte | 30–35% increase | Not measured | 20–25% increase | Cartilage explant |
[18] | 0.0.1 | 1–3 | Chondrocyte | 50% increase | Not measured | 25% increase | Cartilage explant |
[19] | 0.05–0.5 | – | Chondrocyte | Not measured | Not measured | Not measured | Bovine nasal cartilage |
[20] | 1 | – | Chondrocyte | Not measured | Not measured | Not measured | Agarose |
[21] | 1 | 2.5% | Chondrocyte | Increase | Increase | Increase | Agarose gels |
[22] | 0.1 | 3 | Chondrocyte | 30–100% increase | Increase | 100–200% increase | Cartilage explant disks |
[23] | 0.5 | – | Chondrocyte | Not measured | Not measured | Not measured | No scaffolds |
[24] | 0.05 | – | Chondrocyte | Increase | Increase | Not measured | No scaffolds |
[25] | 0.5 | 10–20% | Chondrocyte | Increase | Increase | Increase | Fibrin-polyurethane |