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Table 5 Effect of experimental contact shear on chondrocyte proliferation and matrix composition

From: Shear bioreactors stimulating chondrocyte regeneration, a systematic review

  Hz % strain Cell proliferation Collagen GAG Proteoglycan Scaffold
[15] 1 2 Chondrocyte 40% increase Not measured 25% increase (Cpp) calcium poly phosphate
[16] 0.01 0.4–1.6 Chondrocyte 40% increase Not measured 25% increase Cartilage disk
[17] 0.1 0.5–6 Chondrocyte 30–35% increase Not measured 20–25% increase Cartilage explant
[18] 0.0.1 1–3 Chondrocyte 50% increase Not measured 25% increase Cartilage explant
[19] 0.05–0.5 Chondrocyte Not measured Not measured Not measured Bovine nasal cartilage
[20] 1 Chondrocyte Not measured Not measured Not measured Agarose
[21] 1 2.5% Chondrocyte Increase Increase Increase Agarose gels
[22] 0.1 3 Chondrocyte 30–100% increase Increase 100–200% increase Cartilage explant disks
[23] 0.5 Chondrocyte Not measured Not measured Not measured No scaffolds
[24] 0.05 Chondrocyte Increase Increase Not measured No scaffolds
[25] 0.5 10–20% Chondrocyte Increase Increase Increase Fibrin-polyurethane