Fig 1

Glycolytic metabolism and its functional relevance in PSCs. Acetyl-CoA, acetyl-coenzyme A; ATP, adenosine triphosphate; HIF1, hypoxia-inducible factor 1; HK2, hexokinase 2; LDHA, lactate dehydrogenase; PDH, pyruvate dehydrogenase; PDK1, pyruvate dehydrogenase kinase 1; PKM2, pyruvate kinase M2; PSC, pluripotent stem cell