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Fig. 2 | Inflammation and Regeneration

Fig. 2

From: Roles of fibrinolytic factors in the alterations in bone marrow hematopoietic stem/progenitor cells during bone repair

Fig. 2

Effects of AMD3100 or anti-SDF-1 antibody on the number of HSPCs in the bone marrow after femoral bone damage in mice. The numbers of HSPCs in the bone marrow of the contralateral intact (intact) and damaged (defect) femurs 2 days after femoral bone damage in mice with or without intraperitoneal administration of AMD3100 (5 mg/kg) or local treatment with an anti-SDF-1 antibody (25 μg/body) were enumerated by flow cytometry. The data were expressed as the ratio of HSPC number to that in intact femurs of control mice [7]. The value of vertical axis is 1.0 = 2930 HSPCs/5 × 106 BMCs in contralateral intact femurs in control mice. Data represent the mean ± SEM of 5 mice. *p < 0.05

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Inflammation and Regeneration

ISSN: 1880-8190

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