Fig. 3From: Roles of fibrinolytic factors in the alterations in bone marrow hematopoietic stem/progenitor cells during bone repairRoles of fibrinolytic factors in bone marrow stem cell changes during the repair process after bone injury. Plg (plasmin) induces the production and release of TGF-β from the extracellular matrix via MMP-9 activation after bone injury. SDF-1, expressed by endosteal preosteoblasts, induces the reduction and mobilization of bone marrow HSCsBack to article page