Fig. 1
From: Bromodomain-containing protein 4 regulates interleukin-34 expression in mouse ovarian cancer cells
BET inhibitor JQ1 suppresses IL-34 expression in IL-34-expressing cancer cell lines. a Analysis of Il34 mRNA expression (normalized by Actb, top panel), IL-34 protein concentration in the culture supernatant (middle panel), and cell viability (bottom panel) of mouse ovarian cancer cell lines OV3121, OV3121-RAS4, and HM-1 treated with JQ1 or DMSO (n = 3). NS, not significant; *p < 0.05; Student’s t test. Error bars represent SEM. b Morphologies of the cells treated with DMSO or JQ1. Scale bars 50 μm