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Fig. 4 | Inflammation and Regeneration

Fig. 4

From: Expression of ACE2 and a viral virulence-regulating factor CCN family member 1 in human iPSC-derived neural cells: implications for COVID-19-related CNS disorders

Fig. 4

γ-Secretase inhibitor treatments suppress JUN expression in hiPSC-NS/PCs. a Expression of JUN in hiPSC-NS/PCs (neurospheres) is significantly reduced by treatment with a γ-secretase inhibitor (DAPT or compound 34) (n = 3 independent experiments). As a control sample, dimethyl sulfoxide (DMSO) as a solvent was added instead of GSI. Values in the line graphs represent the mean ± SD.

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