Recent progress in pancreatic islet cell therapy

Table 2 A list of growth factors or chemicals used for generating functional PSC-derived ECs

References		Pagliuca et al., 2014 [19] Millman et al., 2016 [37]	Rezania et al., 2014 [20]	Velazco et al., 2019 [38]
Stages	DE	Activin A	GDF8	Activin A
	DE	CHIR99021	GSK3β inh	CHIR99021
	PG	KGF	FGF7	KGF
	PG		Vitamin C	LDN193189
	PP, EP	LDN193189	Vitamin C	KGF
		KGF	RA	SANT-1
		SANT-1	SANT-1	PDBu
		PDBu	TPB	RA
		RA	LDN	Y27632
		Y27632	Alk5 inh	Activin A
		Activin A	T3
			LDN193189
	EC	SANT-1	Alk5 inh	SANT-1
		RA	T3	RA
		GSXX inh	LDN	GSXX inh
		Alk5 inh	GSXX inh	Alk5 inh
		T3	NAC	T3
		Betacellulin	AXL inh	Betacellulin
		Heparin

ISSN: 1880-8190