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Fig. 2 | Inflammation and Regeneration

Fig. 2

From: Cardiac regeneration by direct reprogramming in this decade and beyond

Fig. 2

Schema of future heart regenerative medicine. The outline of heart regenerative medicine in the case of myocardial infarction is shown. When the heart is damaged due to myocardial infarction, heart failure, and so on, cardiomyocytes are preferentially lost. The fibroblasts of the heart remain and replace the lost cardiomyocytes. Currently, a method of transplanting iPS-derived cardiomyocytes is becoming a reality (upper side). Another method is the transduction of the cardiomyocytes based on the remaining fibroblasts. This is the direct cardiac reprogramming (lower side)

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