Fig. 2
From: Synthesized HMGB1 peptide attenuates liver inflammation and suppresses fibrosis in mice
Therapeutic effects of HMGB1 peptide (1 or 2 weeks of treatment) in the CCl4-induced mouse cirrhosis model. A Schematic of this experiment. B Serum levels of AST, ALT, ALB, and T-Bil on days 63 (1 week of treatment) and 70 (2 weeks of treatment). C Sirius Red staining and quantification of hydroxyproline levels on day 63 (1 week of treatment) and D Sirius Red staining and quantification of hydroxyproline levels on day 70 (2 weeks of treatment). NS, normal saline, n = 8 in each group. Data are presented as means ± standard deviations. ns, not significant. wild, basic data of from undamaged normal liver at the same age