Fig. 5
From: Synthesized HMGB1 peptide attenuates liver inflammation and suppresses fibrosis in mice
Effects of HMGB1 peptide analyzed by single-cell RNA-seq. A Summarized results are shown by Uniform Manifold Approximation and Projection (UMAP) plots. B The numbers of differentially expressed genes (q value < 0.05) in each partition in A are shown. C Reclustered UMAP of macrophage populations. D Frequencies of immune cells in each cluster in A in the normal saline (NS) control and HMGB1 peptide-treated groups. E The frequencies of macrophage subtypes in C in the normal saline (NS) control and HMGB1 peptide-treated groups. F Gene Ontology biological process functional analysis of subtypes 5, 6, and 7. G Gene Ontology analysis using genes that were solely expressed by macrophage subtype 2