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Fig. 17 | Inflammation and Regeneration

Fig. 17

From: Molecular biology of autoinflammatory diseases

Fig. 17

Loss-of-function mutations in immunoproteasome components PSMB8, PSMB4, PSMA3, PSMB9, or proteasome maturation protein (POMP) in patients with PRAAS/NNS/CANDLE. Loss-of-function mutation in immunoproteasome components such as PSMB8, PSMB4, PSMA3, PSMB9, or proteasome maturation protein (POMP) leads to increased secretion of type I IFN by immune cells

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