Table 2 Mouse/rat models or human samples used in the studies introduced in this review

Cardiac fibrosis

 Aortic banding/ascending aortic constriction

[3, 8]

 HFD-induced cardiac fibrosis

[9]

 Myocardial infarction (ligation of the left anterior descending artery)

[8, 10,11,12]

 Myocardial infarction (distal left coronary artery ligation)

[13]

Lung fibrosis

 Tumor-driven fibrosis (Kras and Trp53 deficiency)

[14, 15]

 Bleomycin- and hypoxia-induced PH

[16, 17]

 Monocrotaline (MCT)-induced pulmonary hypertension

[16, 17]

 MCT-induced PAH

[18]

 Radiation-induced fibrosis

[14, 15, 19]

 Sugen or combination of sugen and hypoxia-induced PAH

[20]

 Human lung cancer sampes (small-cell, large-cell, and squamous cell carcinoma and adenocarcinoma)

[14]

 PAH patient-derived MVEC

[21]

Liver fibrosis

 Carbon Tetrachloride CCL4 liver injury model

[22]

 EC-specific deletion of Erg

[22]

 Patient-derived livers with end-stage liver diseases including non-alcoholic steatohepatitis (NASH), primary biliary cholangitis (PBC), and alcohol-related liver disease (ALD)

[22]

Renal fibrosis

 HFD-induced renal fibrosis in EC-specific deletion of Atg5

[9]

 Orthotopic left kidney transplantation model

[23]

 Serum samples from patients with chronic allograft dysfunction

[23]

Atherosclerosis

 ApoE3 Leiden mice (hyperlipoproteinemia/hypercholesterolemic model)

[24]

 High-fat diet-induced atherosclerosis model in ApoE KO mice

[25,26,27,28]

 Disturbed flow-induced atherosclerosis after partial carotid ligation surgery

[29]

 Human samples of atherosclerotic coronary arteries

[30]

 Human advanced atherosclerotic samples

[24]

Transplant arteriopathy, femoral artery injury model, vein graft model

[31]

Diabetes (streptozotocin-induced hyperglycemia)

[32]

Tail lymphedema model

[33]

Tumor EC-derived CAF

 Syngeneic graft tumor

[2, 34]

 Spontaneous mammary tumors

[35]

 Syngeneic graft tumor in EC-specific deletion of Ramp2

[36]

 Syngeneic graft tumor in EC-specific deletion of Ptgds

[37]

 Radiation-induced EndoMT in Kras and Trp53-driven spontaneous lung tumor

[15]

 Samples from patients with lung cancer who received radiotherapy

[15]