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Table 3 In vitro models in the studies introduced in this review. EC subtypes or other cell types co-cultured with EC/cultured in supernatant from EC

From: Emerging roles of inflammation-mediated endothelial–mesenchymal transition in health and disease

Culture model and EC subtype

References

Human

 

 Aortic EC (HAoEC/HAEC)

[24, 29, 32, 38, 39]

 Coronary EC

[3]

 Coronary artery EC (HCAEC)

[13, 39, 40]

 Dermal lymphatic EC (HDLEC)

[33, 41]

 Endothelial colony-forming cells (ECFC)

[21]

 Hepatic sinusoidal EC (HSEC)

[22]

 Juvenile foreskin lymphatic EC

[42]

 Microvascular EC (HMVEC)

[5, 9]

 Umbilical vein EC (HUVEC)

[8, 17, 26, 32, 36, 39, 40, 43,44,45]

 Umbilical artery EC (HUAEC)

[34, 46]

 Pulmonary aortic ECs/human pulmonary artery ECs (HPAECs)

[6, 14, 21, 39, 47]

 Pulmonary microvascular endothelial cell (HPMEC)

[14]

 Pulmonary microvascular endothelial cell (MVEC) from PAH patients

[21]

 Renal glomerular endothelial cell (HRGEC)

[23]

 Skin microvascular EC (HMEC)

[40]

Mouse

 

 Cardiac EC

[27]

 Lung EC

[2, 28]

 EC isolated from infarcted hearts

[10]

 ES-derived EC (MESEC)

[4]

 Mesenteric LEC immortalized by SV40 tsA58T antigen

[33]

 TEC derived from spontaneous mammary tumors

[35]

 TEC derived from human melanoma xenograft

[48]

 TEC derived from syngeneic melanoma and lung carcinoma

[37]

Other animal source

 

 Rat pulmonary arterial EC (PAEC)

[18]

 Bovine aortic EC (BAEC)

[28]

Co-culture/culture with supernatant

 

 Oral cancer cell culture in supernatant from HUAEC undergoing EndoMT

[49]

 Co-culture of mouse aortic endothelial cell (MAEC) with LPS-activated BMDM (macrophage)

[12]

 Co-culture of HUVEC with primary melanoma cells collected from tumors

[36]