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Fig. 6 | Inflammation and Regeneration

Fig. 6

From: Facilitation of colonic T cell immune responses is associated with an exacerbation of dextran sodium sulfate–induced colitis in mice lacking microsomal prostaglandin E synthase-1

Fig. 6

Colonic expression profile of Th17/Th1-related cytokines in mPGES-1−/− mice with DSS-induced colitis. Expressions of mRNA for IL-17A, IFNγ, IL-2, TNFα, IL-1β, IL-6, TGFβ1, IL-23p19, IL-12/23p40, and IL-12p35 in colon from mice treated with 1% DSS for indicated days were analyzed by real-time RT-PCR (n = 7 to 10). Levels of mRNA expression are shown as the fold induction relative to day 0 expression in WT mice (assigned the value “1”). *P < 0.05 vs WT mice within each day, †P < 0.05 vs non-DSS-treated WT mice, and ‡P < 0.05 vs non-DSS-treated KO mice; 2-way ANOVA followed by Tukey multiple comparison test

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Inflammation and Regeneration

ISSN: 1880-8190

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