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Fig. 4 | Inflammation and Regeneration

Fig. 4

From: A novel prostaglandin I2 agonist, ONO-1301, attenuates liver inflammation and suppresses fibrosis in non-alcoholic steatohepatitis model mice

Fig. 4

Effects of ONO-1301 against macrophages in vitro. A Schematic of the experiment. B After addition of lipopolysaccharide (25 ng/ml), ONO-1301 (0.01 μM) to macrophage cultures, mRNA expression levels of Il6, Ccl2, Tnfa, Inos, Il10, and Cd206 were analyzed (each experiment was repeated seven times). C cAMP levels of each condition were analyzed of three independent experiments. Data are presented as mean ± standard deviation. ns: not significant

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