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Fig. 5 | Inflammation and Regeneration

Fig. 5

From: A novel prostaglandin I2 agonist, ONO-1301, attenuates liver inflammation and suppresses fibrosis in non-alcoholic steatohepatitis model mice

Fig. 5

Effects of ONO-1301 against hepatic stellate cells (HSCs) in vitro. A Macroscopic features of HSCs on day 3 with or without ONO-1301. B After addition of ONO-1301 (0.1 μM) or vehicle to HSC cultures, mRNA expression levels of Acta2, Col1a1, Col3a1, Hhip, Ctgb, Hgf, and Vegf were analyzed (each experiment was repeated five to seven times). Scale bar = 100 μm. Data are presented as mean ± standard deviation. ns: not significant

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