Fig. 3
From: A case of refractory systemic lupus erythematosus with monocytosis exhibiting somatic KRAS mutation
Morphology and phenotypic profiles of blood of the patient. A Patient monocytes were sorted by flowcytometry and were Giemsa stained. No abnormalities were found. B Flow cytometric analyses of the blood from healthy donor (HC) and the patient. Top panels show the CD4 and CD8 expression profiles of lymphocyte-gated TCRαβ+ cells. CD4+CD8+TCRαβ+ lymphocyte percentage was higher in the patient than in the HC. Middle panels show the CD14 and CD16 expression profiles in the CD13+ cells (monocyte-gated). CD14+CD16+ monocyte percentage was elevated in the patient compared to the HC. Bottom panels show the CD14 and CD16 expression profiles of HLA-DR-negative cells in the large cells defined by Forward and Side scatter plots (granulocyte-gated). CD14+CD16+ granulocyte percentage was augmented in the patient using the HC as reference