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Fig. 4 | Inflammation and Regeneration

Fig. 4

From: Immune-instructive copolymer scaffolds using plant-derived nanoparticles to promote bone regeneration

Fig. 4

(A) Upper panel: Representative micrographs of hematoxylin/eosin-stained sections from unfunctionalized PLCA scaffolds (Control) and PLCA scaffolds functionalized with PA (PA) at 4 days. Magnification 100×. Lower panel: Histological grading of fibrous tissue capsule and inflammatory cell infiltration at day 4 (early inflammatory response) post implantation of Control and PA scaffolds. Data expressed as average score (*p < 0.05). (B) Upper panel: Representative micrographs of hematoxylin/eosin-stained sections from Control scaffolds and PA scaffolds at 4 weeks. Magnification 400×. Lower panel: Histological grading of fibrous tissue capsule and inflammatory cell infiltration at 4 weeks post-implantation (late inflammatory response) Control and PA scaffolds. Data expressed as average score (*p < 0.05)

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