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Fig. 1 | Inflammation and Regeneration

Fig. 1

From: Osteoclast biology in the single-cell era

Fig. 1

Schematic of the osteoclast culture system. Murine bulk bone marrow cells are treated with M-CSF for 2 days, and then, these cells are stimulated with RANKL in the presence of M-CSF. Osteoclasts appear in the culture system after 3–5 days of RANKL stimulation. The osteoclast culture contains heterogeneous populations of cells, only a portion of which is able to differentiate into mature osteoclasts

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