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Fig. 3 | Inflammation and Regeneration

Fig. 3

From: Therapeutic non-invasive brain treatments in Alzheimer’s disease: recent advances and challenges

Fig. 3

Mitochondrial fission and fusion. Under healthy conditions, the healthy mitochondrial network is maintained by the balance of mitochondria fission (right) and fusion. Drp1 is located in the cytosol, and Fis1 and Mff are located on the outer mitochondrial membrane. Mitochondrial fission occurs when the Fis1 and MFF recruit cytosolic Drp1 to the outer mitochondrial membrane. Mitochondrial fusion is mediated by Mfn1 and Mfn2 from the mitochondrial outer membranes and Opa1 in the mitochondrial inner membranes

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