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Table 1 Human studies of the gut virome in metabolic disorders

From: Characterization of the human gut virome in metabolic and autoimmune diseases

Disease

Study population

References

Obesity

obese subjects (n= 128) and lean controls (n= 101) in China

[39]

Obesity + MetS

obese (n= 10), obese with MetS (n= 8) and normal weight children (n= 10) in Mexico

[40]

Obesity + MetS

obese subjects with MetS (n= 9: self-stool transplant, n= 3; healthy-donor-stool transplant recipients, n= 6) in the Netherlands

[41]

NAFLD

NAFLD patients (n= 73: NAS of 0–4, n= 29; NAS of 5–8 or liver cirrhosis, n= 44) and controls without liver disease (n= 9) in Germany

[42]

T2DM

T2DM patients (n= 71) and nondiabetic controls (n= 74) in China

[43]

T2DM + Obesity

T2DM patients with obesity (n= 74) and lean controls (n= 101) in China

[39]

T2DM

T2DM patients (n= 17) and nondiabetic controls (n= 29) in China

[44]

CVD

coronary heart disease inpatients (n= 37) and healthy residents without a history of CVD (n= 6) in China

[45]

CVD

atherosclerotic CVD patients (n= 218) and healthy controls (n= 187) in China

[46]

Hypertension

hypertension patients (n= 99), prehypertension (n= 56) and healthy controls (n= 41) in China

[47]

  1. Abbreviations: MetS Metabolic syndrome, NAFLD Non-alcoholic fatty liver disease, NAS NAFLD Activity Score, T2DM Type 2 diabetes mellitus, CVD Cardiovascular disease.