Fig. 11

Neuroinflammation and neural cell death in the hippocampus. a Quantification of the number of Iba1-positive cells in the granular layer (n = 4, each group, control vs. severe SAH; p = 0.043, sham vs. severe SAH; p = 0.062). b Quantification of the number of Iba1-positive cells in the hilus (n = 4, each group, control vs. severe SAH; p = 0.085, sham vs. severe SAH; p = 0.097). c Representative immunostaining images of Iba1-positive cells (red) in the hippocampi of mice in the control, sham, mild SAH, and severe SAH groups. Scale bar, 100 μm. d Quantification of the number of dead neural cells in the granular layer (n = 3, each group. e Representative confocal images of TUNEL (green) and NeuN (red) in the hippocampus. Scale bar, 100 μm. Statistical analyses were performed with one-way ANOVA and Tukey–Kramer post hoc tests. The values in the bar graphs represent the mean ± SE. NS: not significant