Skip to main content
Fig. 8 | Inflammation and Regeneration

Fig. 8

From: Subarachnoid hemorrhage triggers neuroinflammation of the entire cerebral cortex, leading to neuronal cell death

Fig. 8

As the severity of SAH worsens, neuronal cell death increases in the cerebral cortex in the anterior region of the cerebrum (1.0 mm anterior to bregma). a Cells that were positive for both NeuN and TUNEL were quantified to assess neuronal cell death. The number of dead neural cells in layers I to III of the anterior region of the cerebrum was quantified (n = 3, each group). b Quantification of the number of dead neural cells in layers IV to VI of the anterior region of the cerebrum (n = 3, each group). c Quantification of the number of dead neural cells in all layers of the anterior region of the cerebrum (n = 3, each group). d Representative confocal images of TUNEL (green) and NeuN (red) in the anterior cortex. Nuclei were counterstained with Hoechst (blue). Scale bar, 50 μm. Statistical analyses were performed with one-way ANOVA and Tukey–Kramer post hoc tests. The values in the bar graphs represent the mean ± SD. **p < 0.01, ***p < 0.001. NS: not significant

Back to article page