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Fig. 7 | Inflammation and Regeneration

Fig. 7

From: Resolving the conflicts around Par2 opposing roles in regeneration by comparing immune-mediated and toxic-induced injuries

Fig. 7

Par2 promotes regeneration in hepatocytes after CCl4 injection. WT mice recovered from the tissue damage caused by CCl4 while Par2KO mice failed to recover. A, F, and K. WT mouse before CCl4 injection. B, G, and L. WT 1 day after injection: fat vacuoles (arrows) indicate hepatic steatosis. C, H, and M. WT 7 days after injection: the tissue recovered. D, I, and N. Par2KO mice 1 day after CCl4 injection: fat vacuoles (arrows) indicate hepatic steatosis. E, J, and O. Par2KO mice 7 days after injection: necrotic lesions (E, J) and collagen fibers (O in pink) appeared. A-E. Macroscopic images. F-J. H&E, K-O. Sirius Red. Scale bar = 50μm

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Inflammation and Regeneration

ISSN: 1880-8190

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